Martin acquires a dingy warehouse after killing the owner named Jake and begins abducting people to use for his own human centipede. Martin keeps a pet centipede, which he gleefully feeds. Sebring, Martin's psychiatrist, also touches him inappropriately and prescribes him heavy medication. Short, obese, asthmatic, and mentally challenged Martin lives with his overbearing and emotionally abusive mother, who despises him and constantly blames him for having his father put in prison for physically and sexually abusing Martin when he was a boy. In the tollbooth of a parking garage in East London, Martin Lomax is watching The Human Centipede (First Sequence) on his laptop, a film he is obsessed with, complete with his own scrapbook composed of images and scenes from the original film.

It was critically panned, with much criticism focused on its acting, plot, and violence, although Harvey's performance received some praise.

It was subject to heavy censorship throughout the world, where it was sometimes edited to remove objectionable content or banned altogether. The Human Centipede 2 (Full Sequence) received substantial attention and controversy for its graphic depictions of violence, sexual violence and body horror. Harvey as a psychiatrically and intellectually impaired English man who watches and becomes obsessed with the first Human Centipede film, and decides to make his own 'centipede' consisting of 12 people, including Ashlynn Yennie, an actress from the first film. An international co-production of the Netherlands and the United Kingdom, and the sequel to Six's 2009 film The Human Centipede (First Sequence), the film stars Laurence R. The Human Centipede 2 (Full Sequence) is a 2011 exploitation body horror film written, directed, and co-produced by Tom Six.

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